ABSTRACT
Violacein is an important natural antimicrobial pigment that is mainly produced by Chromobacterium violaceum and Janthinobacterium lividum. It presents a significant range of effects against phytopathogenic and human fungi, besides being featured as having low toxicity, and by its important ecological role in protecting amphibian species and applications in dyed medical fabric. The hypothesis about violacein's action mechanisms against mucormycosis (Rhizopus arrhizus) and candidiasis (Candida auris) is herein discussed based on data available in the scientific literature.
Subject(s)
Anti-Infective Agents , Antifungal Agents , Antifungal Agents/pharmacology , Chromobacterium , Fungi , Humans , IndolesABSTRACT
In a severe COVID-19 patient case (78-year old male) that was under active immunotherapy for high-grade non-muscle invasive bladder cancer was followed. He received a shorter hospitalization period, as hypothesis it was suggested that active immunotherapy played a crucial role together to anti-inflammatory and antiviral treatment in precluding the evolution of pulmonary symptoms to a poor prognosis.